B7-H7 (HHLA2)/TCR Activator CHO Cell Line

●Purchase●DescriptionRecombinantCHO-K1cellsstablyexpressinghumanB7-H7(alsoknownasHHLA2:HERV-HLTR-associatingprotein2

產品型號：78321
廠商性質：生產廠家
更新時間：2023-11-11
訪問量：336

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Description

Recombinant CHO-K1 cells stably expressing human B7-H7 (also known as HHLA2: HERV-H LTR-associating protein 2, GenBank accession #NM_007072) and an engineered T cell receptor (TCR) activator. B7-H7 mediates an immune-stimulatory signal via TMIGD2 (Transmembrane and immunoglobulin domain containing 2) in na?ve T cells while delivering an immune-inhibitory signal through KIR3DL3 in activated T cells and Natural Killer (NK) cells.

Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.

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Synonyms

HERV-H LTR-associating protein 2, Human endogenous retrovirus-H long terminal repeat-associating protein 2, B7y, B7H7, B7-H5, B7-H7

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Product Data Gallery

Activation of KIR3DL3/IL-2 Luciferase Reporter Jurkat cells in response to increasing doses of anti-HHLA2 antibody when co-cultured with B7-H7 (HHLA2)/TCR Activator CHO cells in the presence of TCR agonist anti-CD28.

TMIGD2/NFAT Luciferase Reporter Jurkat Cell Line activity in response to increasing doses of anti-HHLA2 antibody when co-cultured with B7-H7 (HHLA2)/TCR Activator CHO cells.

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B7-H7 (HHLA2)/TCR Activator CHO Cell Line

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